Plasma Fractionation Market in terms of revenue was estimated to be worth $26.5 billion in 2022 and is poised to reach $36.3 billion by 2027, growing at a CAGR of 6.5% from 2022 to 2027. The market size is updated for the base year of 2021 and forecasted from 2022 to 2027 by studying the impact of the overall plasma fractionation industry. The new version of the report includes ranges and scenarios, value chain analysis, ecosystem analysis, technology analysis, patent analysis, trends and disruptions impacting customers, Porter’s five forces analysis, and a regulatory landscape. In the earlier version of the report, 20 companies were profiled. In the updated version, a total of 25 companies have been profiled. Market growth is driven mainly by factors such as the growing use of immunoglobulins in various therapeutic areas, the rapidly growing geriatric population, and the rising prevalence of respiratory diseases and alpha-1-antitrypsin deficiency (AATD). However, high costs, limited reimbursements, and the market disruption caused by recombinant alternatives are expected to restrain the growth of this market to a certain extent during the forecast period.
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Key Market Players
The plasma fractionation market is an oligopolistic market. The prominent players operating in this market include CSL (Australia), Grifols, S.A. (Spain), Shire (US), Octapharma AG (Switzerland), Kedrion S.P.A (Italy), LFB (France), Biotest AG (Germany), Sanquin (Netherlands), China Biologic Products Holdings Inc. (China), GC Pharma (Korea), Bio Products Ltd. (UK), Japan Blood Products Organization (Japan), Emergent BioSolutions (US), Shanghai Raas Blood Products Co., Ltd. (China), Intas Pharmaceuticals Ltd. (India), Bharat Serum Vaccines Limited (India).
Drivers: Growing use of immunoglobulins for various therapeutic area
The increasing use of immunoglobulins for various therapeutic areas, such as autoimmune diseases, immune deficiencies, and infectious diseases, is driving the growth of the plasma fractionation market. Immunoglobulins are proteins produced by the immune system to fight against infections, allergies, and other diseases. Plasma fractionation processes are used to extract immunoglobulins from the plasma of healthy donors. These immunoglobulins are then used to treat various diseases, such as primary immunodeficiencies, autoimmune diseases, and infectious diseases. In addition, the increasing demand for immunoglobulins in the research sector is also driving the growth of the plasma fractionation market.
Restraints: Use of recombinant alternatives for certain plasma products
The use of recombinant alternatives for certain plasma products such as factor VIII, IX and von Willebrand factor is a key restraint for the growth of the plasma fractionation market. The advent of recombinant alternative products has enabled more efficient and cost-effective treatment of hemophilia, while also eliminating the risk of infections associated with the use of plasma-derived products. Numerous companies, such as Novo Nordisk, have launched recombinant alternative products in the market, which has significantly impacted the market of plasma-derived products.
Opportunities: Increased risk of communicable disease
The increasing risk of communicable diseases such as influenza, coronavirus, and HIV is expected to drive demand for plasma fractionation products. According to the World Health Organization (WHO), the number of reported cases of communicable diseases such as HIV, malaria, and tuberculosis has been increasing consistently over the past few decades. This has necessitated the need for more efficient and effective treatments and therapies for these diseases, which is expected to drive the demand for plasma fractionation products in the coming years.
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North America was the largest regional market for plasma fractionation market in 2021
The global plasma fractionation market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. In 2021, North America accounted for the largest share of the plasma fractionation market, followed by Europe and the Asia Pacific. The large share of North America in the global market is attributed to the growing number of hemophilic patients in the region and the increasing use of immunoglobulins for PID, chronic inflammatory demyelinating polyneuropathy (CIDP), idiopathic thrombocytopenic purpura, pediatric HIV, allogenic bone marrow transplantation, and B-cell chronic lymphocytic leukemia. However, the market in the Asia Pacific is expected to grow at the highest CAGR during the forecast period. This can be attributed to the growth in the overall healthcare industry, increasing number of hemophilic patients, increasing number of organ transplantations, increasing focus on diagnosis and prophylactic treatment, increasing awareness about technologically advanced products, and improving the standard of living in several APAC countries.
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