Major Growth Driving Factors:
Over the course of the forecast period, the global market for peptide synthesis is anticipated to expand at a CAGR of 7.4%. The expanding therapeutic applications, technological advancements in peptide synthesis, and rising peptide demand are driving growth in this market. In addition, increased spending on R&D, a thriving industry, and the use of peptides in pharmaceutical products are some of the key factors expected to propel market expansion. Nonetheless, over the course of the forecast period, the absence of a single set of regulations pertaining to therapeutic peptides and the high cost of instruments are anticipated to impede the market’s growth.
Driver: Peptides are being used in pharmaceutical products more often.
Peptides are very specific and very active pharmaceutical ingredients. They have a wide range of therapeutic applications because of the diversity of their biological functions. Because of their wide molecular space, high biological activity, high specificity, ease of synthesis, accessibility, and low toxicity, peptides are making their way into the drug development process as possible active pharmaceutical ingredients.
Because of their therapeutic potential, high specificity and low toxicity, versatility and diversity, improvements in peptide synthesis technologies, potential use as drug candidates, emergence of personalized medicine, and rising interest in and funding for peptide-based therapeutics, peptides are becoming more and more common in the pharmaceutical industry. All of these elements work together to make peptides a more valuable class of molecules in the creation of innovative and focused pharmaceutical treatments.
Opportunity: Creation of personalized medicines
The peptide synthesis industry has significant growth opportunities due to the emergence of personalized medicine. Peptides provide the necessary targeting, customization, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technologies, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
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Restraint: High cost of instruments
The synthesis of proteins involves the use of rapid, high-throughput systems. Peptide synthesizers and chromatography equipment with advanced features and functionalities are generally priced at a premium. Peptide synthesizers are either fully automated, manual, or semi-automated and offer users complete control over the synthesis process. The cost of peptide synthesizers ranges from USD 300,000 to 250,000 based on the automation and advanced features accommodated. Such high prices of instruments make it difficult for developing countries to venture into peptide synthesis.
Challenge: Issues associated with the route of administration of peptide drug
The majority of therapeutic peptides are administered by the parenteral route because of insufficient absorption from the gastrointestinal tract. Peptide drugs are usually indicated for chronic conditions, and the use of injections on a daily basis during long-term treatment has significant drawbacks. In contrast to this inconvenient and potentially problematic method of drug administration, the oral route offers advantages such as self-administration with a high degree of patient acceptability and compliance. The main reasons for the low oral bioavailability of peptide drugs are pre-systemic enzymatic degradation and poor penetration of the intestinal mucosa.
Key Stakeholders:
# Life sciences instrumentation and reagent companies
# Pharmaceutical and biotechnology companies
# Proteomics database and software providers
# Peptide service providers
# Research and consulting firms
# Academic medical centers
# Government research organizations
# Clinical research institutes
# Contract Research Organizations
Market Size Estimation:
A top-down approach was used to estimate and validate the total size of the peptide synthesis market. This method was also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:
# The key players in the industry and market have been identified through extensive secondary research
# The revenues generated from the peptide synthesis business of leading players have been determined through primary interviews and secondary research
# All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources
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Projected Revenue Growth, Globally:
The global peptide synthesis market in terms of revenue was estimated to be worth $601 million in 2023 and is poised to reach $859 million by 2028, growing at a CAGR of 7.4% from 2023 to 2028.
Geographical Growth Scenario:
Asia Pacific is likely to grow at the highest growth rate during the forecast period.
Based on the region, peptide synthesis market is segmented into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. North America is the largest regional segment. The Asia Pacific region is estimated to grow at the highest CAGR in the peptide synthesis market during the forecast period. The growth of the pharmaceuticals and life sciences market in the region is primarily driven by the rising R&D expenditure, especially in the area of drug discovery & development, the rising prevalence of chronic disease conditions, and significant investments in the development of therapeutics mAbs.
