According to research report the global tangential flow filtration market is experiencing strong growth, according to a new report from MarketsandMarkets. The market was valued at $1.9 billion in 2023 and is projected to reach $3.6 billion by 2028, expanding at a compound annual growth rate (CAGR) of 13.5%.
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Several key factors are driving the rise of the TFF market, including increasing research and development spending by pharmaceutical and biotechnology companies, continuous improvements in filtration technologies, and growing demand for biologics. TFF is an essential step in processing biologics such as proteins, antibodies, and vaccines. As more biologics receive regulatory approval, the need for effective TFF solutions also increases.
Recent technological advancements are making TFF systems more efficient, convenient, and cost-effective. These include single-pass TFF, automated systems, enhanced fouling control, and better integration with downstream purification processes like chromatography. Key players in the market are actively developing such innovative products. For example, in 2021 Repligen acquired companies specializing in single-use fluid management technologies to expand its TFF product portfolio.
However, the TFF market growth faces some restraints as well. Alternative technologies like centrifugation and microfiltration compete with TFF in certain applications. Additionally, interactions between proteins and charged excipients during filtration can introduce complexities and impact process efficiency.
Currently, North America dominates the global TFF market due to the strong presence of leading biopharma companies and technology providers in the region. But Asia-Pacific is anticipated to exhibit the fastest growth over the forecast period owing to expanding biomanufacturing capabilities and increasing chronic disease prevalence in countries such as China and India.
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Overall, with rising biologics demand and advancing filtration technologies, the TFF market is poised for robust double-digit growth over the next several years. Key players in the market include Danaher, Merck KGaA, and Sartorius AG.
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